BALTIMORE - Leave it to the youngest person in the lab to think of the Big Idea. Xuyu Qian, 23, a third-year graduate student at Johns Hopkins, was chatting in late January with Hongjun Song, a neurologist. Song was wondering how to test their three-dimensional model of a brain - well, not a brain, exactly, but an
‘‘organoid,’’ essentially a tiny ball of brain cells, grown from stem cells and mimicking early brain development. ‘‘We need a disease,’’ Song said. Qian tossed out something he’d seen in the headlines: ‘‘Why don’t we check out this Zika virus?" Within a few weeks, that suggestion led to one of the most significant findings in efforts to answer a central question: How does the Zika
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